By Hugh E. Huxley (auth.), H. E. D. J. Ter Keurs MD, PhD, J. V. Tyberg MD, PhD (eds.)
This quantity constitutes the court cases of a satellite tv for pc symposium of the XXXth congress of the overseas Union of Physiological Sciences. The symposium has been held In Banff, Alberta Canada July Sep 11 1986. this system used to be geared up to supply a selective review of present advancements in cardiac biophysics, biochemistry, and body structure. with a view to spotlight parts of enhance ing principles and to stimulate the individuals' inquisitiveness into the character and complexity of the built-in cardiovascular method, lectures and discussions have been provided that emphasised evolving and occasionally provocative ideas within the box. With an analogous target in brain we now have, for the readers of this quantity, in short summarized the final discussions. we want to thank a number of contributors whose commitment made this sym posium and book of the lawsuits attainable. Mrs. Lois Kokoski and Mrs. Madeleine Aldridge of the convention place of work of the collage of Calgary likely without problems dealt with the main points of the symposium. Peter de Tombe, Dr. Peter Backx and Dr. Jeroen Bucx transcribed the overall discussions. ultimately, we enjoy the additional attempt of our secretaries, Lenore Doell and Gregory Douglas, and the paintings of Anna Tyberg who ready the ultimate manuscripts for ebook. Henk E.D.J. ter Keurs, M.D. Ph.D. John V. Tyberg, M.D. Ph.D.
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22. : Isotonic velocity transients in frog muscle fibres following quick changes in load. J. Physiol. 319: 219-238, 1981. 23. : The maximum length for contraction in vertebrate striated muscle. J. Physiol. 156: 150--165, 1961. 24. : The sliding filament/cross-bridge theory: a critical review. Physiol. Reviews 63: 1049-1113, 1983. 25. : Connecting filaments, core filaments, and side-struts: a proposal to add three new load-bearing structures to the sliding filament model. In: Contractile Mechanisms in Muscle.
It is certainly the dissatisfaction with this theory that has prompted the emergence of the very many alternative theories that have appeared. The late Graham Hoyle, in his recent book, describes 'Why muscle scientists lose knowledge'. In the context of the work presented here, his views are probably worth pondering . References 1. : Comments on Quantal mechanisms. in cardiac contraction. Circ. Res. 59: 9-14, 1986. 2. : Quantal mechanisms in cardiac contraction. Circ. Res. 59: 1-8, 1986. 3.
I~' . I~IIII~ nl' ! I.. ' . I . ' . : ..... t" I: . rl I . , .. , . ·1 :.... . . . / .... , . . . . . . . . . . I I' I' I. I: II . 1, " . • i· • • • . • • • • , . :. :. :. :·-:. , :. ·:,·:' :. ~-~-;·,:. ·:·~;;i~l . ',. "...... I ............ · ,... •...... --- " " " " " " " 10 seC Figure 3-4. Violent oscillations of damaged myofibrils. Bullfrog atrium myofibrils, when some of the sarcomeres suffer minor damages, tend to fall into a tug-of-war between healthy and damaged sarcomeres.
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