By Paul G. Schmitz
An leading edge, organ-specific textual content that blends simple technology with the basics of medical medicine
Part of the Human Organ structures series, Renal: An built-in method of Disease skillfully bridges the space among the technology and perform of medication. This superbly illustrated ebook seamlessly integrates the middle parts of mobile biology, anatomy, body structure, pharmacology, and pathology, with medical medication. it's the excellent better half for scientific scholars transitioning to their medical years, in addition to training physicians who want a effortless replace at the easy technological know-how underlying the perform of scientific medicine.
Features and highlights include:
• distinct studying targets sincerely country studying goals
• middle content material emphasizes strategies and contains the newest advancements within the field
• superbly illustrated with designated legends to elucidate very important or tricky concepts
• plentiful scientific instance bins spotlight the scientific implications of easy science
• each one bankruptcy is followed by way of an annotated bibliography to supply an outline of the severe literature within the field
• A bulleted precis on the finish of every bankruptcy highlights the "big picture" and allows practise for standardized exams
• End-of-chapter case-based questions with unique motives make stronger very important innovations and check mastery of the material
Medical scholars and citizens will locate Renal: An built-in method of Disease a useful learn consultant for an organ-system established curriculum. The booklet additionally serves as a great primer for postgraduate citizens coming into a nephrology fellowship application.
Read Online or Download Renal: An Integrated Approach to Disease (1st Edition) PDF
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Extra info for Renal: An Integrated Approach to Disease (1st Edition)
The ﬂatter (shorter cells) are representative of the distal tubular epithelium. 15B only: Courtesy of Dr. ) collecting duct cells reveal a small number of organelles and almost no invaginations of the basal cell membrane. The inner medullary collecting duct consists of intercalated cells (<10%) and a unique cell type simply referred to as the inner medullary collecting duct (IMCD) cell. The IMCD cell is involved in the terminal regulation of sodium, chloride and water homeostasis. 16 Electron micrograph reveals a normal principal cell (PC) in panel A and type A (acid secreting) and type B (bicarbonate secreting) intercalated cells (IC) in panel B.
Madsen KM, Tisher CC. Structural-functional relationship along the distal nephron. Am J Physiol. Jun 1986;250(6, pt 3): F1-15. Excellent discussion of the techniques used to study nephron function. Describes the structural heterogeneity along the distal nephron, especially the collecting duct. Thoughtful analysis of the major cell types observed in the distal tubule and collecting duct. 3. Gumbiner B. Structure, biochemistry, and assembly of epithelial tight junctions. Am J Physiol. Dec 1987;253 (6, pt 1):C749-758.
Renal Interstitium The interstitium of the kidney consists of connective tissue and cells. The interstitial volume is relatively scant compared to the tubules and glomeruli (<10% of the total). Some interstitial cells resemble fibroblasts and control the synthesis and secretion of extracellular matrix. These cells are believed to play a pivotal role in the development of renal fibrosis in diseases characterized by progressive loss of renal function. Phagocytic cells are also present in the interstitium.
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